Pro-inflammatory cytokines and chemokines upregulated in plasma of Dengue fever patients
Dengue virus generally causes an acute self-limited illness known as classic dengue fever, lasting 5-7 days. Symptoms include high fever, headache, retro-orbital headache, myalgia, arthralgia, abdominal pain, nausea and vomiting. A minority of patients (less than 3%) develop dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS), the most severe form. Dengue is the most frequent human vector-borne viral disease.