Sensitivity of RT-LAMP system for the detection of Paralysis

  • Andrade Clemente
Keywords: Paralysis, RT-LAMP system, clinical samples, RNA purification


Among currently available procedures detecting RNA viruses, a reverse transcription-loop-mediated isothermal amplification (RT-LAMP) system seems to be a most promising method that meet the demands expected for the cell culture-based isolation procedure. In this study, we have developed a RT-LAMP system for a rapid and highly sensitive detection of enterovirus including PV directly from stool samples of AFP cases without cell culture-based procedures.