Treatment of Hemorrhagic Shock Patients with Dextran Combined With Hypertonic Sodium Chloride and Predictive Nursing

  • Chengli Zhou
Keywords: Dextran; Hypertonic sodium chloride; Acute hemorrhagic shock; Adverse drug reactions


This article was to observe the clinical efficacy and safety of dextran injection combined with hypertonic sodium chloride injection in the treatment of acute hemorrhagic shock. Forty-two patients with acute hemorrhagic shock were randomly divided into control group and experimental group.The control group was given hypertonic sodium chloride injection, intravenous infusion for 5 ~ 15min; the experimental group was given 20mL kg-1 dextran 40 sodium chloride injection on the basis of the control group, intravenous infusion for 15 ~ 30min. Systolic blood pressure (SBP), hematocrit (Hct), high cut (HBV), medium cut (MBV), low cut (LBV), whole blood viscosity (WBV), and shock index were compared between the two groups. SI), as well as the occurrence of adverse drug reactions.The results showed that after treatment, the SBP of the experimental group and the control group were (105.12±10.63) and (92.41±9.73) mmHg, respectively, and Hct were (56.15±3.15)% and (40.58±4.13)%, respectively, and HBV was (3.26). ±0.37) and (3.72±0.49) mPas, MBV were (3.66±0.48) and (5.17±0.62) mPas, respectively, and LBV were (6.68±0.85) and (7.72±1.25) mPa s, respectively. All were statistically significant (all P>0.05). The adverse drug reactions in the control group were mainly mild chest tightness, and the adverse drug reactions in the test group were mainly itching.Conclusion: Dextran injection combined with hypertonic sodium chloride injection can effectively increase the blood pressure of patients with acute hemorrhagic shock, correct the state of shock, improve hemodynamic parameters, and increase the incidence of adverse drug reactions.