Effect of PiCCO-guided CRRT Fluid Management on the Prognosis of Critically Ill Patients

  • Fulin Hu
Keywords: Pulse indicator continuous cardiac output; Continuous renal replacement therapy; Fluid management; Critical illness; Prognosis


To retrospectively analyze the guiding function of pulse indicator continuous cardiac output (PiCCO) in continuous renal replacement therapy (CRRT) and the effect on the prognosis of critically ill patients. All case data were collected from 85 critically ill patients who were treated with CRRT in the emergency intensive care unit (EICU) of our hospital from January 2015 to August 2018. Among them, 40 patients receiving monitoring of PiCCO through central venous catheters and arterial catheters were included in PiCCO group and 45 patients receiving monitoring of central venous pressure (CVP) through central venous catheters were included in the control group. The major clinical interventions, changes in acute physical and chronic health examination (APACHE II) scores and the prognosis were recorded.Compared with the control group, the resuscitation fluid volume within 72 hours was significantly smaller, the time of using antibiotics, mechanical ventilation time, length of ICU stay and length of hospital stay were significantly shorter in PiCCO group (P<0.05). Compared with the control group, the APACHE II scores at 12h, 24h and 72h after treatment were significantly lower in PiCCO group (P<0.05). The incidence rates of volume-related hypotension, pulmonary edema, Lac>2mol/l and 28-day mortality rate in PiCCO group (7.50%, 5.00%,10.00%, 10.00%) were significantly lower than those in the control group (24.44%, 20.00%,, 28.89%, 28.89%) (P<0.05). Compared with CVP, PiCCO guided CRRT can effectively improve the effects of fluid resuscitation, reduce complications and improve the prognosis of critically ill patients.