Changes of Electrolyte, Coagulation Function and Blood Gas Index before and after Massive Blood Transfusion and Clinical Value

  • Yongxia Liu
Keywords: Massive blood transfusion; Electrolyte; Blood gas index; Coagulation function


This paper observes and compares the changes of electrolyte concentration; blood gas index and coagulation function before and after massive blood transfusion, and to study the clinical value of these changes. Thirty-six patients who underwent massive blood transfusion in our hospital from June 2017 to June 2018 were selected as the study subjects. Serum electrolyte concentrations of Na+, Ca2+, Cl-, K+, prothrombin activity time (APTT), bleeding time (TT), coagulation time (PT) and fibrinogen (F) were compared before and after massive blood transfusion. The changes of blood gas indexes such as blood coagulation function index, arterial blood PH value, alkali residue (BE), blood lactic acid (Lac), total CO2, etc. Result: After massive transfusion, the concentration of K+, Ca2+ decreased significantly; 15 patients had hypokalemia, accounting for 41.67%, 24 patients had hypocalcemia, accounting for 66.67%, 23 patients had acidemia, accounting for 63.89%; PT, APTT, TT increased significantly, FIB decreased; after transfusion, BE increased, Lac value and CO2 were obvious. The difference was significant (P < 0.05). There was no significant difference in PH value, Na+, Cl- between before and after transfusion (P > 0.05). A large amount of blood transfusion will cause electrolyte imbalance in patients, which will lead to complications such as hypokalemia, hypocalcemia and acidemia, and easily lead to coagulation dysfunction. Clinical nurses should pay close attention to the changes of electrolyte and coagulation function of patients during blood transfusion.