Reliability of Endoscopic Biopsy and Endoscopic Resection in the Diagnosis of Gastric Intraepithelial Neoplasia

  • Xiaoyan Chen
Keywords: Endoscopic biopsy; Pathological diagnosis; Gastric intraepithelial neoplasia; Endoscopic resection


This paperanalyzes the value of endoscopic biopsy and endoscopic resection pathology in the diagnosis of gastric intraepithelial neoplasia. A retrospective analysis was made of 80 cases of intraepithelial neoplasia diagnosed by gastroscopic biopsy in our hospital from March 2014 to April 2018. Among them, 15 cases were diagnosed as low grade intraepithelial neoplasia (LGIN), 55 cases were diagnosed as high grade intraepithelial neoplasia (HGIN), and 10 cases were diagnosed as early gastric cancer (EGC). Endoscopic resection was performed in all cases. The difference rate and related factors were analyzed according to the pathological features of gastroscopic biopsy and endoscopic resection. The overall difference in preoperative biopsy and endoscopic resection was 53.8% (43/80). 15 cases of LGIN diagnosed by preoperative biopsy were confirmed as advanced cancer after operation, 5 cases were diagnosed as HGIN, the difference rate was 33.3%, 3 cases were diagnosed as EGC, the difference rate was 20%; preoperative biopsy diagnosis 55 cases of HGIN, 3 cases of LGIN were confirmed after operation, the difference rate was 5.5%, 32 cases of EGC, the difference rate was 58.2%; 10 cases of EGC diagnosed by preoperative biopsy, postoperative confirmed pathological maintenance. The preoperative biopsy and postoperative pathological differences were related to the two factors of lesion diameter > 2 cm and surface hyperemia (χ2=14.434, 11.116, P<0.05).Endoscopic resection should be the main pathological diagnosis and treatment for intraepithelial neoplasia. The reliability of preoperative biopsy is not good.