Expression of Plasma Brain Natriuretic Peptide and Cardiac Function in Patients with Valvular Heart Disease during Perioperative Period

  • Fei Chen
Keywords: Cardiac valvular disease; Perioperative period; Plasma brain natriuretic peptide; Cardiac function

Abstract

This paper analyses the relationship between the expression of plasma brain natriuretic peptide (BNP) and cardiac function in patients with valvular heart disease during perioperative period. Result shows Plasma BNP levels were significantly different in patients with different cardiac function grading, which was statistically significant (P<0.05). The higher the cardiac function grade, the higher the plasma BNP level. The overall difference of plasma BNP levels in patients at different time points was very significant. Compared with the preoperative period, plasma BNP levels were significantly increased at 24 h after surgery, 48 h after surgery, and 7 days after surgery, and the data were significantly different. P<0.05 was statistically significant. The longer the ventilator assisted use time, the higher the patient's plasma BNP level. There were 7 patients with severe arrhythmia after operation, and 48 patients without severe arrhythmia. The plasma BNP level in patients with severe arrhythmia was significantly higher than that in patients without severe arrhythmia. The relationship between the expression of plasma brain natriuretic peptide level and cardiac function in patients with valvular heart disease is very close. The changes of plasma BNP level in patients can accurately reflect the cardiac function, which is significant for preoperative evaluation and postoperative treatment.

Published
2020-01-01