Experimental Study on Repairing Peripheral Nerve Injury with Spiral Modified Nerve End Suture

  • Xuecheng Wang
Keywords: Spiral; Nerve end suture; Nerve injury; Peripheral nerve

Abstract

This paper explores the clinical efficacy of spiral modified nerve end suture in the treatment of peripheral nerve injury growth factors. The group of patients received an intravenous injection of 0.5 mg of Acobalamine. It lasts once a day for 10 days. Then, 0.5 mg of mecobalamin was changed to oral administration three times a day for one course of treatment. The course of treatment is 3 to 6 weeks. 50 patients in the control group, once a day, the course of treatment was 30 micrograms, intramuscular injection of nerve growth factor. The course is 3 to 6 weeks. In group C, 50 patients received mecobalamin (0.5 mg, intravenously, once a day) in combination with nerve growth factor (30 mg, intramuscularly, once a day). The treatment lasts for 3 to 6 weeks. The aim was to observe the therapeutic effects of two different drugs on patients with peripheral nerve injury. The effect of spiral modified nerve end suture combined with nerve growth factor in the treatment of peripheral nerve injury in group C was significantly better than that in group A and B alone. The results of the three groups of treatments are compared as follows. For the recovery of sensory above grade 2, the efficacy of group C was generally better than that of group A and group B, and the approximate chi-square test was H = 13.6573, P = 0.11. Regarding the recovery of exercise, the recovery of grade V in group A and group C was statistically significant, H = 3.8431, P = 0.499, while there was no significant difference in group B (P > 0.05). Spiral modified nerve end suture combined with nerve growth factor has a certain curative effect on peripheral nerve injury, and has important clinical significance.

Published
2020-01-01