Analysis of the immunological factors of HIV-1 Infection

  • Cacilda Lima
Keywords: HIV-1 Infection, immune activation, immunodeficiency, Clinical Trials


As biomarkers for HIV-1 infection, plasma HIV-1RNA concentration reflectsthemagnitudeofviralreplication and the CD4+ T lymphocyte count represents the resulting end-organ damage or immunodeficiency. An additional major component of HIV-1 pathogenesis is immune system activation, reflecting a dysregulated host immune response to HIV-1 infection and its sequelae.