Bcl-10 and Survivin Protein Expression in the Prognosis of Gastric MALT lymphoma

  • Jin Wang
Keywords: Gastrointestinal mucosa associated lymphoid tissue; Lymphoma; Bcl-10 protein; Survivin protein

Abstract

This paper explores the value of bcl-10 and survivin protein expression in the prognosis of patients with
gastrointestinal mucosa associated lymphoid tissue (MALT) lymphoma.There was no significant correlation
between the gender and age of patients with gastric MALT lymphoma and the positive expression of bcl-10 and
survivin protein (P > 0.05). The depth of invasion, lymph node involvement and tumor size affected the
expression of bcl-10 protein (P < 0.05). In addition, the survivin protein was also affected by the histological
type of patients (P The positive rates of ivin protein expression in patients with stage Ⅲ were significantly
higher than that in patients with stage Ⅰ and stage Ⅱ (P < 0.05); the positive rates of bcl-10 and survivin protein
expression in patients with high malignant gastric MALT lymphoma were significantly higher than those in
patients with low malignant gastric MALT lymphoma (P < 0.05); the positive rates of both proteins in patients
with relapse after treatment were higher than those in patients without relapse (P < 0.05). The expression of bcl-
10 and survivin protein is related to tumor size, invasion degree, clinical stage and pathological stage in patients
with gastric MALT lymphoma. The detection results can be used as an important reference index to evaluate the
prognosis of patients, which is worth popularizing.

Published
2020-01-01