Relationship between PRKAA2 Gene Polymorphism and the Efficacy of NBP in Patients with Cerebral Infarction

  • Qun Zhang
Keywords: PRKAA2 gene polymorphism; NBP; Cerebral infarction


This paper analyzes the relationship between PRKAA2 gene polymorphism and the efficacy of NBP in patients with cerebral infarction. The study selected 211 patients with cerebral infarction admitted to our hospital from January 2017 to January 2018. All patients were treated with Enppu. The NIHSS score was used to evaluate the therapeutic effect of patients. The AMPKα2 gene was labeled by gene sequencing and analyzed. The relationship between efficacy.The distribution frequencies of rs1124900, Rs17848595 and Rs1418442 genotypes were different. The GS type of rs1124900 ineffective group was higher than that of the effective group. The AA type of Rs17848595 ineffective group was higher than that of the effective group, and the Rs1418442C allele was lower than the effective group. Activation of AMPK is a key indicator of recovery after cerebral ischemia and hypoxia.