Clinical Effect of Zhimi Kang Suppository on Cervicitis Patients with HPV Infection and the Influence of Inflammatory Factors

  • Hongcai Fan
Keywords: Cervicitis; Human papillomavirus; Zhimi kangshuan; Inflammatory factors; Clinical efficacy


This paper explores the clinical effect of Zhimi Kang suppository in the treatment of cervicitis combined with human papillomavirus (HPV) infection and its influence on the level of inflammatory factors.All patients were divided into observation group and control group by random number table method, with 50 patients in each group. Two groups of patients need to be treated with microwave and antiviral therapy. The observation group is treated with Zhimi Kang suppository at the same time. The clinical effect of the two groups after treatment and the influence on serum inflammatory factor hypersensitive C-reactive protein (hs CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF - α) are compared. The duration of abnormal vaginal secretions and wound healing time in the observation group were (16.6 ± 3.9) d, (9.8 ± 2.1) d, significantly lower than those in the control group (20.1 ± 4.7) d, (11.3 ± 3.0) d, (P < 0.01); after treatment, the levels of serum hs CRP, IL-6 and TNF - α in the observation group were (3.04 ± 0.85) mg / L, (16.27 ± 4.85) pg / ml, (22.15 ± 5.18) pg / ml, significantly lower than those in the control group. The difference was significant (P < 0.01) between the two groups (3.76 ± 1.01) mg / L, (20.13 ± 5.03) pg / ml, (25.36 ± 5.86) pg / ml), and the level of serum inflammatory factors in the two groups was significantly lower than that before treatment (P < 0.001); after treatment, the negative rate of HPV in the observation group was 94%, significantly higher than that in the control group (P < 0.05); the effective rate of the observation group was 94%. %The difference was significant (P < 0.01). The treatment of cervicitis combined with HPV infection with Zhimi Kang suppository can improve the clinical efficacy and reduce the level of inflammatory factors.