Risk Factors of Diabetic Ketoacidosis with Acute Renal Injury

  • Dan Li
Keywords: Ketoacidosis, Acute kidney injury, Risk factors


This paper explores the clinical characteristics and risk factors of diabetic ketoacidosis (DKA) complicated with
acute renal injury (AKI), so as to provide evidence for clinical prevention and improvement of prognosis of AKI.
We screened DKA patients hospitalized in our hospital from January 2016 to December 2017, and divided them
into AKI group and non AKI group (Naki group) according to whether AKI occurred, and compared the clinical
characteristics and laboratory data of the two groups. To analyze the risk factors of AKI in DKA patients and
evaluate the correlation between AKI and risk factors. The incidence of AKI in 339 DKA patients was 33.6%,
and the in-hospital mortality of AKI patients was 1.975 times that of non AKI patients. Elevated triglyceride (or
= 0.066), low-density lipoprotein (or = 0.186) and proteinuria (or = 3.52) were independent risk factors for AKI
in DKA patients (all < 0.05). Aki was positively correlated with cholesterol, triglyceride, LDL and proteinuria (r
= 0.237, 0.240, 0.224, 0.325, P < 0.05). The incidence of AKI was higher in DKA patients. The increase of
triglyceride, LDL and proteinuria were independent risk factors for AKI in DKA patients. Active control of
blood lipid level and urinary protein is very important to prevent AKI in DKA patients.