Effects of Dexmedetomidine in Combination with Ropivacaine Spinal Anesthesia on Elderly Patients Undergoing Lower Limb Surgery

  • Wenyu Yao
Keywords: Ropivacaine; Dexmedetomidine; Elderly patients; Spinal anesthesia

Abstract

To compare the efficacy of intrathecal ropivacaine in combination with 5μg dexmedetomidine on elderly
patients undergoing lower limb surgery. Sixty patients aged between 64 and 86 years old of ASA I-III scheduled
for lower limb surgery were enrolled, including 35 males and 25 females. They were randomized divided in
two groups with 30 cases in each group. Group A received 15mg ropivacaine and 10% glucose liquor to a total
amount of 2.5mL. Group B received 15mg ropivacaine combined with 5μg dexmedetomidine and 10% glucose
liquor to a total amount of 2.5mL. The changes in the blood pressure and heart rate before and after anesthesia
were observed and recorded. The characteristics and duration time of onset and regression of sensory and motor
blockade were recorded; at the same time, the side effects were observed. Result: The anesthetic pain of all
patients was relieved. The degree and duration of sensory blockade in Group A were lower and shorter than
those in Group B (p<0.01). The degree and duration of motor block in Group A were lower and shorter than
those in Group B (p<0.01). Conclusion: Dexmedetomidine combined with ropivacaine results in an increased
duration and efficacy of analgesia, and the duration time of onset and regression of sensory and motor blockade
was longer than that in Group B and was associated with no obvious adverse effects.

Published
2020-01-01