Application of Hemagglutinase for Injection in Otolaryngology Head and Neck Surgery

  • Yue Liang
Keywords: Hemagglutinase; Otolaryngology head and neck surgery; Drug application


This paper explores the application effect of hemagglutinase for injection in otolaryngology head and neck surgery.180 patients who underwent Otolaryngology Head and Neck surgery from February 2017 to March 2018 in our hospital were selected as the subjects of this study. They were divided into hemagglutinase group and sodium chloride group. In each of the 90 patients, hemagglutinase was injected into the hemagglutinin group 30 minutes before and after surgery, and 0.9% sodium chloride solution was administered to the sodium chloride group 30 minutes before and after surgery. The coagulation function index, hemostasis time, blood loss, unit area blood loss and liver and kidney function indexes were observed and compared between the two groups. There were no significant changes in coagulation function index and liver and kidney function indexes between the two groups. The difference was not statistically significant (P<0.05). The hemostatic time, blood loss and blood loss per unit area of the hemagglutinin group were significantly lower than that of sodium chloride. Group (P < 0.05). In the treatment of otolaryngology, head and neck, injection hemagglutinase can effectively improve the bleeding of wounds during and after surgery, reduce the amount of bleeding, shorten the bleeding time, better curative effect, and the patient has no adverse symptoms and high safety.