Steroepidemiologic study of Human Herpesvirus 6 infection in transplant patients

  • Rossano Bruna
Keywords: Human Herpesvirus 6, myelosuppression, hepatitis, Hematopoietic Stem Cell Transplantation


Approximately 95% of adults have anti–human herpesvirus 6 (HHV-6) serum antibodies or detectable HHV-6 DNA in saliva or PBMC samples. Primary infection occurs during early childhood. After primary infection, HHV-6 remains latentexceptduring periods of immune suppression. HHV-6 reactivates in 33%–48% of patients who undergohematopoieticstem cell transplantation (HSCT).