Therapeutic Effect of Creatine Phosphate and Sodium Fructose Diphosphate on Children with Myocarditis and Its Effect on Serum Cardiac Troponin I

  • Duandan Han
Keywords: Myocarditis; Sodium fructose diphosphate; Creatine phosphate; Serum cardiac troponin I

Abstract

Phosphocreatine and fructose diphosphate have been widely used as clinical protective agents for heart function
in children with myocarditis, but the specific effects of the two are controversial. 72 children with myocarditis
were divided into control group and observation group according to different treatment methods. In the control
group, children were treated with phosphocreatine, and the patients in the observation group were treated with
sodium fructose diphosphate. The efficacy and serum cardiac troponin I, lactate dehydrogenase 1, aspartate
aminotransferase, peripheral blood creatine isoenzyme levels and adverse reactions were compared between the
two groups. Results The total effective rate of the observation group was 96%, which was higher than 75% of
the control group. Serum cardiac troponin I, lactate dehydrogenase 1, aspartate aminotransferase, and peripheral
blood creatine isoenzyme levels in the observation group were lower than those in the control group, and the
difference was statistically significant (P<0.05). There was no significant difference in the incidence of total
adverse reactions between the two groups. In children with myocarditis, treatment with sodium fructose
diphosphate can improve the curative effect, optimize the serum cardiac troponin I level, and have fewer
adverse reactions, which can be clinically promoted and applied.

Published
2020-03-01