Adverse Reactions of Insulin Injection in the Treatment of Diabetes Mellitus and Effect of Standardized Nursing on Life Quality

  • Guizhen Zou
Keywords: Diabetes mellitus; Insulin; Adverse drug reactions; Neuropathy


To analyze the clinical manifestations of insulin in the treatment of diabetic adverse reactions, and to explore the relationship between different kinds of insulin and the incidence of hypoglycemia, so as to improve the awareness of prevention. Fang Gu analyzed the clinical data of adverse reactions in diabetic patients treated with insulin, and compared with the incidence of hypoglycemia. The results showed that the most adverse reactions were hypoglycemia (20%), weight gain (8%), systemic or local allergic reactions (2%), facial and lower extremity edema (2%); other rare adverse reactions were adipose tissue hyperplasia, somongyi phenomenon, fat atrophy and insulin resistance. The incidence and severity of hypoglycemia were the highest in intensive insulin therapy; the incidence of hypoglycemia was also closely related to different varieties of insulin when insulin was combined with oral sulfonylurea (P<0.01). Hypoglycemia is the most common adverse reaction of insulin, followed by weight gain and allergic reaction, which should be paid attention to. The incidence and degree of hypoglycemia are closely related to insulin varieties and treatment methods. The key measures are to select varieties and actively prevent them.