Effect of Eucalyptus Limonensis on Serum TGF- 1, IL-8 and T Lymphocyte Subsets in Patients with Nasopharyngeal Carcinoma

  • Xu Lu
Keywords: Keywords nasopharyngeal carcinoma; Eucalyptus limonensis; Serum transforming factor-β 1; Interleukin-8; T lymphocyte subsets

Abstract

The effect of IMRT on serum tgf-31 and T-lymphocyte subsets in patients with NPC was studied. The control group and the observation group were treated with two-dimensional Eucalyptus limonensis and IMRT respectively. The 5-year survival rate, recurrence, adverse reactions, serum tgf-31, L-8 and T-lymphocyte subsets were compared before and after treatment. The results showed that the regional recurrence free survival rate and tumor free survival rate of the patients in the observation group were significantly higher than those in the control group, the local recurrence rate of the patients in the observation group was significantly lower than that in the control group, and the distant metastasis free survival rate of the patients in the observation group was slightly higher than that in the control group; the total incidence of adverse reactions in the process of Eucalyptus limonipin in the control group was 41%, and that in the observation group was 32%; the serum tgf-31 and IL-8 levels of the patients in the two groups after treatment were higher than those in the control group. The level of CD8 after treatment was significantly lower than that before treatment (P < 0.05). Conclusion: IMRT has a significant effect on NPC, which may be achieved by improving the levels of serum tgf-31, IL-8 and T lymphocyte subsets.

Published
2020-03-01