Evaluation of the Therapeutic Effect of Low Dose Heparin on Thrombophlebitis of Lower Extremity after Operation

  • Yaowen Chang
Keywords: Lower extremity thrombus; Phlebitis; Low molecular weight heparin; Intravenous micro continuous infusion

Abstract

Thrombophlebitis of lower extremity is a common complication after operation, which not only affects the
quality of life of patients, but also has a high rate of disability and death. In this paper, we studied the value of
low molecular weight heparin in the treatment of thrombophlebitis of lower extremity. Low molecular weight
heparin is composed of D-glucose, amine residue and glucosamine. It has the functions of anticoagulant factor
Xa, antiplatelet and anticoagulant factor IIA. It can promote the release of fibrinolytic enzyme activator and
enhance the antithrombotic effect of endothelial cells. The patients in the control group received hypodermic
injection of LMWH, while the patients in the observation group received continuous intravenous infusion of
LMWH. The therapeutic effect and adverse reactions of the two groups were compared. Results the total
effective rate of the observation group was higher than that of the control group. The incidence of adverse
reactions in the observation group was 12% lower than that in the control group (23%) (P < 0.05). Low
molecular weight heparin (LMWH) continuously pumped into the vein has a significant effect in the treatment
of thrombophlebitis of lower extremity after operation, with few adverse reactions, which has the value of
popularization and application.

Published
2020-03-01