Effect of Calcitriol Combined with Calcic D on Bone Metabolism and Therapeutic Effect in Postmenopausal Osteoporosis

  • Jinde Li
Keywords: Calcic D; Calcitriol; Postmenopausal women; Osteoporosis

Abstract

In this paper, the effect of calcitriol combined with calq-d on bone metabolism and therapeutic effect in postmenopausal osteoporosis was studied. The process of bone turnover or bone metabolism is actually the process of osteoclasts absorbing bone and osteoblasts for new bone synthesis. The metabolic indexes related to bone formation include ALP, osteocalcin, etc., and the urinary calcium / creatinine (CA / Cr), urinary hydroxyproline / creatinine, etc. related to bone absorption. The control group was treated with calq-d alone, and the study group was treated with calq-d combined with calcitriol to observe and compare the bone metabolism level, pain degree and quality of life before and after treatment. The results showed that before treatment, there was no significant difference in bone metabolism indexes among the groups. After treatment with different methods, the indexes of the study group were superior to those of the control group, with statistical significance (P < 0.05); after treatment, the VAS score of the study group was lower than that of the control group; after treatment, the scores of the indexes of the quality of life of the study group were higher than that of the control group, with statistical significance (P < 0.05). The combination of calcic D and calcitriol can improve the quality of life of postmenopausal women.

Published
2020-03-01