Clinical Value of Ultrasonography in the Diagnosis of Fetal Malformation

  • Ke Sun
Keywords: Chromosomal abnormality; Four-dimensional ultrasound; NT; Congenital fetal malformation


NT thickening is closely related to fetal aneuploid chromosome karyotype abnormality, and also related to fetal cardiovascular system abnormality, skeletal malformation, lymphoid system development disorder, fetal death in utero, abortion and so on. It is an effective index for the diagnosis of fetal malformation generally confirmed in clinical practice. In this paper, the value of fetal nuchal translucency thickness (NT) combined with four-dimensional color Doppler ultrasound in the diagnosis of fetal malformation was studied. The results showed that 47 cases of abnormal fetuses were diagnosed, 45 cases of abnormal fetuses were detected by NT, the accuracy rate of diagnosis was 96%, including 12 cases of lymphangiocystoma, 20 cases of fetal death and 13 cases of fetal abnormal development, 50 cases of abnormal fetuses were confirmed and the difference was detected by four-dimensional ultrasound in 1230 cases of pregnancy of 22-28wk 50 cases were normal fetus, the accuracy rate of diagnosis was 100.0%. It is helpful to evaluate the risk of Down's syndrome by detecting the thickness of nuchal translucency with ultrasonography from 11 to 14 weeks of gestation, and it is helpful to detect the structural abnormality of fetus by four-dimensional ultrasonography from 22 to 28 weeks of gestation. The combined detection of the two is of great clinical significance for screening the congenital malformation of fetus.