Relationship between Serum Prealbumin Levels and Levels of Inflammatory Factors and Myocardial Enzymes in Patients with Acute Myocardial Infarction

  • Chengsheng Xu
Keywords: Acute myocardial infarction; Serum prealbumin; Inflammatory factor; Myocardial enzyme

Abstract

To investigate the relationship between serum prealbumin levels and levels of inflammatory factors and
myocardial enzymes in patients with acute myocardial infarction (AMI). As the AMI group, 72 healthy subjects
from our hospital were selected as the control group. Elbow venous blood was collected from all standard
subjects at admission, pre-albumin was detected by immunoturbidimetric assay, troponin T, interleukin-6 and
interleukin-8 were detected by electrochemiluminescence, and creatine kinase was determined by rate method.
Isozyme, C-reactive protein was detected by latex-enhanced immunoturbidimetric assay. The serum prealbumin
levels, inflammatory factor levels and myocardial enzyme levels were observed and compared. The relationship
between serum prealbumin and its various indicators was analyzed by Pearson linear correlation. The PA level
(0.23±0.14) in the AMI group was lower than that in the control group (0.30±0.09) g/L. The difference between
the two groups was statistically significant (t=3.26, P<0.05). The interleukins in the AMI group. -6
(38.05±22.45) ng/L, interleukin-8 (295.62±98.71) ng/L, troponin T (4.81±2.9) μg/L, creatine kinase isoenzyme
(244.5±165.54) U/L And C-reactive protein (6.68±3.57) mg/L water level was significantly higher than that of
the control group (6.13±3.42) ng/L, (17.24±7.41) ng/L, (0.06±0.07) μg/L, (12.24 ±5.25) U/L, (2.26±1.54) mg/L,
the difference was statistically significant (P<0.05); according to Pearson correlation analysis, serum prealbumin
and troponin T, interleukin-6 in patients with AMI Interleukin-8, creatine kinase isoenzyme and C-reactive
protein were positively correlated (r value was 0.000, P value was <0.05), and the correlation coefficients were
close to 1, and the correlation was strong.Conclusion: Serum prealbumin levels are positively correlated with
inflammatory factor levels and myocardial enzyme levels. The study of serum prealbumin expression has a
clinical diagnostic value for acute myocardial infarction.

Published
2020-05-01