Phylogenetic perspectives of innate immune system

  • Andrea Gerardo
Keywords: Innate immune system, Drosophila, mannosebinding Lectins, autoimmune diseases


The ability to respond to infectious agents is a prerequisite for the survival of multicellular organisms. Recent
findings indicate that the basic tenets of mammalian first-line host defenses have their origin in primitive life forms.
Remarkably, a set of protein motifs and structures are conserved from plants through insects to humans.