Human Leukocyte Antigen for invasive Streptococcus pyogenes infections

  • Maldonado Mariela
Keywords: Streptococcus pyogenes, Microbial superantigens, proteins, antigen processing

Abstract

Streptococcal toxic shock syndrome is triggered by exotoxins of Streptococcus pyogenes that function
immunologically as superantigens. Microbial superantigens are a family of proteins with particular structural and
sequence features that result in the shared ability to bypass the mechanisms of conventional, major
histocompatibility
complex–restricted antigen processing.

Published
2020-05-01