Genetic polymorphism Pharmacology to alter patient’s risk of toxicity

Abstract

Medical treatment of critical care patients is challenging because of the complexity of many acute illnesses, which
necessitates their admission to intensive care units, and the frequent presence of multiple, simultaneous maladies.
For example, an individual patient may concurrently receive multiple antibiotics, antifungal agents, sedativeanalgesics,
antiarrhythmics, anticoagulants, paralytics, and medications to suppress secretion of gastric acid.