Clinical Effect of Paroxetine Combined with Alprazolam in the Treatment of Diabetes Mellitus with Anxiety and Depression

  • Dehuan Kong
Keywords: Paroxetine; Alprazolam; Diabetes mellitus with anxiety and depression

Abstract

The clinical effect of paroxetine alone or combined with alprazolam in the treatment of diabetes mellitus with
anxiety and depression. The control group patients were treated with paroxetine alone, the study group patients
were treated with paroxetine and alprazolam, and the clinical effect of the two groups was compared. There was
no significant difference in FPG, 2hPG and ACTH between the two groups before the treatment (P > 0.05); after
the treatment, the two groups were significantly lower than before the treatment (P < 0.05); after the treatment,
the reduction degree of the study group was better than that of the control group, the difference was statistically
significant (P < 0.05). The results showed that there was no significant difference between the two groups
before and after treatment (P > 0.05); after treatment, there was a significant decrease in the two groups
compared with before treatment, the difference was statistically significant (P < 0.05); after treatment, the
research group was significantly better than the control group, the difference was statistically significant (P <
0.05). The incidence of adverse reactions was 21.21% in the study group and 36.36% in the control group. The
clinical efficacy of paroxetine alone or combined with alprazolam in the treatment of diabetes mellitus with
anxiety and depression is better. After treatment, the blood glucose and endocrine level of the patients can be
improved, the anxiety and depression of the patients can also be improved, and the incidence of adverse
reactions is low, and the safety of use is high.

Published
2020-05-01