Efficacy of Mifepristone and GnRH-a in Patients with Endometriosis after Operation

  • Yanping Wang
Keywords: Mifepristone; GnRH-a; Endometriosis; Postoperative effect

Abstract

The effect of mifepristone and GnRH-a on patients with endometriosis after operation. After the drug treatment,
the cumulative recurrence rate of non misoprostone group and GnRH-a group was 18.18% and 21.21%, P >
0.05 between the two groups, and 33.33% between the two groups, P < 0.05. After treatment, FSH, LH and
other hormone indexes in mifepristone group were compared with those before treatment (P > 0.05), while E2
levels were compared with those before treatment (P < 0.05); FSH, LH, E2 levels in GnRH-a group were
compared with those before treatment (P < 0.05), and those in mifepristone group were compared with those
after treatment (P < 0.05). After treatment, the complete remission rate of the patients in the non misoprostone
group and the GnRH-a group were 51.52% and 55.88%, respectively, P > 0.05 for the comparison between the
groups, and 36.36% for the comparison between the patients in the non misoprostone group and the GnRH-a
group, P<0.05 for the comparison between the two groups. There was no significant difference between the two
groups (P> 0.05). Mifepristone and GnRH-a have good effect on patients with endometriosis after operation.
They can effectively reduce the recurrence rate and adverse reactions after EMT.

Published
2020-05-01