Clinical Effect of Dexmedetomidine in Cardiopulmonary Bypass Heart Valve Replacement on Myocardial Function

  • Chunyan Wang
Keywords: Cardiac valve replacement with cardiopulmonary bypass; Dexmedetomidine; Myocardial function

Abstract

To investigate the clinical effect of dexmedetomidine in cardiopulmonary bypass valve replacement on
myocardial function. The control group was given normal saline and the observation group was given
dexmedetomidine. The indexes of myocardial injury, hemodynamics and improvement of cardiac function were
compared between the two groups. CK-MB, cTnI and H-FABP in the observation group were lower than those
in the control group in different periods (P < 0.05); the stability of each blood dynamic blood in the observation
group was significantly better than that in the control group (P < 0.05); the improvement of the overall cardiac
function in the observation group was better than that in the control group. The application of dexmedetomidine
in cardiopulmonary bypass heart valve replacement can reduce the myocardial injury after CPB, promote the
improvement of cardiac function, and have little effect on hemodynamics.

Published
2020-05-01