Underlying disorders and innate immunity response of patients with infectious disease

  • Enrique Urrea
Keywords: Sepsis, innate response, infection, biochemical mediators, clinical syndrome


Sepsis is defined as the systemic host response to infection. To the clinician, the word conjures up a life threatening
clinical syndrome that arises through the innate response to infection. However, sepsis is not a single disease but is
an intricate and heterogeneous process expressed through the interaction of a complex network of biochemical
mediators and amplification cascades.