Clinical Effect and Nursing Intervention of Doxofylline in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease

  • Yi Zhang
Keywords: Doxofylline; chronic obstructive pulmonary disease; Nursing intervention in acute exacerbation period; Clinical effect; Blood gas index

Abstract

To explore the clinical effect and nursing intervention of doxofylline in the treatment of acute exacerbation of
COPD. From February 2018 to January 2019, 60 patients with acute exacerbation of chronic obstructive
pulmonary disease (COPD) were selected and divided into two groups according to the admission sequence, 30
in each group. The control group was treated with conventional medicine, the observation group was treated
with doxofylline combined with nursing intervention in the aggravating period, and the clinical effect, changes
of pulmonary function and arterial blood gas indexes before and after treatment, adverse reactions and patients'
satisfaction were observed. There was no significant difference in FEV1, FEV1 / FVC%, PaO2, PaCO2 and SaO2
between the two groups before treatment (P > 0.05). After treatment, the improvement of each index in the
observation group was better than that in the control group (P < 0.05); the clinical effect in the observation
group was higher than that in the control group (P > 0.05), the total incidence of adverse reactions in the
observation group was higher than that in the control group (P > 0.05); the patients' satisfaction in the
observation group was higher than that in the control group (P > 0.05). Doxofylline and nursing intervention in
the treatment of acute exacerbation of chronic obstructive pulmonary disease do have significant efficacy, high
safety and great application value.

Published
2020-05-01